Prof Erick Strauss (Project leader, SU) will be leading a multi-site, African-based drug discovery project with co-investigators Prof Adrienne Edkins (Rhodes University), Prof Andrew Whitelaw (SU) and Dr Miquel Duran-Frigola (Ersilia Open Source Initiative), as well as collaborators from SU, University of Johannesburg and University of Cape Town. This three-year project forms part of The Gram-Negative Antibiotic Discovery Innovator (Gr-ADI), a first-of-its-kind consortium funded by The Gates Foundation, Novo Nordisk Foundation, and the Wellcome Trust. Gr-ADI will bring together 18 research teams from across the world will openly share data and learnings and work collectively to accelerate the discovery of urgently needed antibacterials for the treatment of infections by Gram-negative bacteria, one of the leading drivers of AMR-related deaths worldwide

The successful candidate will form an integral part in the establishment of a multidisciplinary team that will pursue the discovery and development of novel Gram-negative antimicrobials that induce the targeted degradation of high-value proteins in Klebsiella spp. and potentially other Enterobacteriaceae.

See details here.

Prof Erick Strauss (Project leader, SU) will be leading a multi-site, African-based drug discovery project with co-investigators Prof Adrienne Edkins (Rhodes University), Prof Andrew Whitelaw (SU) and Dr Miquel Duran-Frigola (Ersilia Open Source Initiative), as well as collaborators from SU, University of Johannesburg and University of Cape Town. This three-year project forms part of The Gram-Negative Antibiotic Discovery Innovator (Gr-ADI), a first-of-its-kind consortium funded by The Gates Foundation, Novo Nordisk Foundation, and the Wellcome Trust. Gr-ADI will bring together 18 research teams from across the world will openly share data and learnings and work collectively to accelerate the discovery of urgently needed antibacterials for the treatment of infections by Gram-negative bacteria, one of the leading drivers of AMR-related deaths worldwide. 

Successful candidates will form an integral part in the establishment of a multidisciplinary team that will pursue the discovery and development of novel Gram-negative antimicrobials that induce the targeted degradation of high-value proteins in Klebsiella spp. and potentially other Enterobacteriaceae.

See details here.

A postdoctoral fellowship in the SARChI project: “Mechanistic modelling of health and epidemiology” is currently available in the field of “Mechanistic modelling of insulin sensitivity in skeletal muscle cells”. Applications from suitable candidates are invited for this post for a period of one year, which may be renewable for a further year based on satisfactory performance (annual performance reviews will be held) and the availability of funds.

See details here.

The Protein Folding Research Group with the Department of Biochemistry at Stellenbosch University is seeking a highly motivated Postdoctoral Fellow with strong expertise in computational biology, bioinformatics, and biophysics to join a multidisciplinary project investigating molecular chaperones and protein quality control mechanisms in Plasmodium parasites. This project integrates computational modelling, bioinformatics, and single-molecule biophysical approaches to understand how protein aggregation is regulated and how these pathways may be exploited for drug discovery.

See details here.